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Ion Channel and Receptor Ligands‚ Venoms‚ Toxins and Alkaloids
Latoxan© January 2008 NewsLetter.
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BIOTOXAN®-P01 is a selection of natural molecules from 19 different plant families of Central Asia steppe.
It is a ready-to-use kit made of 2 separate 96-well-plates, for a total 160 molecules.
Each well contains 500 µg of high purity (90 to 98 %) compounds: alkaloids, terpenoids, proanthocyanosids, phytoestrogens…
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New bioactive molecules for HTS in the fields of cancerology, pain relief, haematology, cardiology, multiple sclerosis, Alzheimer’s disease.
KITOXAN® is a unique selection of snakes, scorpions, amphibians and spiders venoms fractions divided in a ready-to-use kit made of 5 separate 96-well-plates. All venoms have been cleared from molecules over 8.500 Da (cytotoxic enzymes) and split up in 20 fractions.
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Each fraction is expected to contain 5 to 10 peptides at a 10µmol concentration in 100µl.
HPLC Chromatogram and MALDI-TOF mass spectrum of each venom are also provided.
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Exclusive !
The most potent Na+ channel activator.
BTX is the most active alkaloid binding at receptor site-2 on sodium channels. It activates the sodium channel even at very negative membrane potentials and keeps it open permanently by preventing channel inactivativation.
Related link :
Batrachotoxin (BTX) on PubMed (More than 500 references).
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Exclusive!
The first discovered CPP (cell penetrating peptide). An activator of Ca2+ release channel / ryanodine receptors,
Maurocalcin is an agonist of ryanodine receptor type 1, 2 and 3 – It potently and reversibly modifies channel gating behaviour of the type 1 ryanodine receptor (RyR1) by inducing increased opening probabilities and a prominent subconductance behaviour.
Read more...
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Best regards
Latoxan
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Sales Contact :
Phone : +33.(0)475.41.91.91
Fax : +33.(0)475.41.91.99
Email : contact@latoxan.com
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© 2007 Latoxan. All rights reserved. You received this editorial/commercial e-newsletter from Latoxan because the information for your account indicates that Latoxan may contact you via e-mail. To unsubscribe from this e-newsletter
please click on the unsubscribe link above or send your request to Latoxan - 20
rue Léon Blum - 26000 Valence - France. Unsubscribe
Ref. : January 2008 NewsLetter - 16/01/2008 09:54:32
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