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Search batrachotoxin



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Items 1 -100 of 100

1:
Tikhonov DB.
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Abstract[Mechanisms of action of voltage-gated sodium channel ligands]
Ross Fiziol Zh Im I M Sechenova. 2007 May;93(5):531-43. Russian.
PMID: 17650621 [PubMed - indexed for MEDLINE]
2:
Duan Y, Zheng J, Nicholson RA.
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AbstractVanilloid (subtype 1) receptor-modulatory drugs inhibit [3H]batrachotoxinin-A 20-alpha-benzoate binding to Na+ channels.
Basic Clin Pharmacol Toxicol. 2007 Feb;100(2):91-5.
PMID: 17244257 [PubMed - indexed for MEDLINE]
3:
Liberatore AM, Schulz J, Favre-Guilmard C, Pommier J, Lannoy J, Pawlowski E, Barthelemy MA, Huchet M, Auguet M, Chabrier PE, Bigg D.
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AbstractButyl 2-(4-[1.1'-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain.
Bioorg Med Chem Lett. 2007 Mar 15;17(6):1746-9. Epub 2006 Dec 22.
PMID: 17234409 [PubMed - indexed for MEDLINE]
4:
Wang SY, Tikhonov DB, Zhorov BS, Mitchell J, Wang GK.
Related Articles, Compound via MeSH, CoreNucleotide (RefSeq), Gene, Gene (GeneRIF), Nucleotide (RefSeq), Protein (RefSeq), Substance via MeSH, Taxonomy via GenBank, UniGene, UniSTS, GEO Profiles, LinkOut
AbstractSerine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel.
Pflugers Arch. 2007 May;454(2):277-87. Epub 2007 Jan 5.
PMID: 17205354 [PubMed - indexed for MEDLINE]
5:
Wang SY, Mitchell J, Wang GK.
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AbstractPreferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel.
Pain. 2007 Jan;127(1-2):73-83. Epub 2006 Sep 7.
PMID: 16962240 [PubMed - indexed for MEDLINE]
6:
Errington AC, Coyne L, Stohr T, Selve N, Lees G.
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AbstractSeeking a mechanism of action for the novel anticonvulsant lacosamide.
Neuropharmacology. 2006 Jun;50(8):1016-29. Epub 2006 Apr 18.
PMID: 16620882 [PubMed - indexed for MEDLINE]
7:
Wang GK, Edrich T, Wang SY.
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Free Full TextTime-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
J Gen Physiol. 2006 Mar;127(3):277-89.
PMID: 16505148 [PubMed - indexed for MEDLINE]
8:
Popa MO, Lerche H.
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Free Full TextCu2+ (1,10 phenanthroline)3 is an open-channel blocker of the human skeletal muscle sodium channel.
Br J Pharmacol. 2006 Apr;147(7):808-14.
PMID: 16432503 [PubMed - indexed for MEDLINE]
9:
Duan Y, Zheng J, Law V, Nicholson R.
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AbstractNatural products from ginseng inhibit [3H]batrachotoxinin A 20-alpha-benzoate binding to Na+ channels in mammalian brain.
Eur J Pharmacol. 2006 Jan 13;530(1-2):9-14. Epub 2005 Dec 15.
PMID: 16359658 [PubMed - indexed for MEDLINE]
10:
Wang SY, Mitchell J, Tikhonov DB, Zhorov BS, Wang GK.
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Free Full TextHow batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis.
Mol Pharmacol. 2006 Mar;69(3):788-95. Epub 2005 Dec 14.
PMID: 16354762 [PubMed - indexed for MEDLINE]
11:
Riddall DR, Leach MJ, Garthwaite J.
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Free Full TextA novel drug binding site on voltage-gated sodium channels in rat brain.
Mol Pharmacol. 2006 Jan;69(1):278-87. Epub 2005 Oct 11.
PMID: 16219909 [PubMed - indexed for MEDLINE]
12:
Tikhonov DB, Zhorov BS.
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AbstractSodium channel activators: model of binding inside the pore and a possible mechanism of action.
FEBS Lett. 2005 Aug 15;579(20):4207-12.
PMID: 16083886 [PubMed - indexed for MEDLINE]
13:
LePage KT, Goeger D, Yokokawa F, Asano T, Shioiri T, Gerwick WH, Murray TF.
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AbstractThe neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons.
Toxicol Lett. 2005 Aug 14;158(2):133-9. Epub 2005 Apr 9.
PMID: 16039402 [PubMed - indexed for MEDLINE]
14:
Berra-Romani R, Blaustein MP, Matteson DR.
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Free Full TextTTX-sensitive voltage-gated Na+ channels are expressed in mesenteric artery smooth muscle cells.
Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H137-45.
PMID: 15961372 [PubMed - indexed for MEDLINE]
15:
Fitch RW, Daly JW.
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AbstractPhosphorimaging detection and quantitation for isotopic ion flux assays.
Anal Biochem. 2005 Jul 15;342(2):260-70.
PMID: 15950910 [PubMed - indexed for MEDLINE]
16:
Cronin NB, O'Reilly A, Duclohier H, Wallace BA.
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AbstractEffects of deglycosylation of sodium channels on their structure and function.
Biochemistry. 2005 Jan 18;44(2):441-9.
PMID: 15641768 [PubMed - indexed for MEDLINE]
17:
Nau C, Wang GK.
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AbstractInteractions of local anesthetics with voltage-gated Na+ channels.
J Membr Biol. 2004 Sep 1;201(1):1-8. Review.
PMID: 15635807 [PubMed - indexed for MEDLINE]
18:
Chevalier E, Petoux F, Chovet M, Langlois A.
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AbstractBeneficial effect of trimebutine and N-monodesmethyl trimebutine on trinitrobenzene sulfonic acid-induced colitis in rats.
Life Sci. 2004 Dec 3;76(3):319-29.
PMID: 15531383 [PubMed - indexed for MEDLINE]
19:
Kong KH, Chen Y, Ma X, Chui WK, Lam Y.
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AbstractTraceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels.
J Comb Chem. 2004 Nov-Dec;6(6):928-33.
PMID: 15530120 [PubMed - indexed for MEDLINE]
20:
Bosmans F, Maertens C, Verdonck F, Tytgat J.
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AbstractThe poison Dart frog's batrachotoxin modulates Nav1.8.
FEBS Lett. 2004 Nov 5;577(1-2):245-8.
PMID: 15527793 [PubMed - indexed for MEDLINE]
21:
Tan J, Liu Z, Wang R, Huang ZY, Chen AC, Gurevitz M, Dong K.
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Free Full TextIdentification of amino acid residues in the insect sodium channel critical for pyrethroid binding.
Mol Pharmacol. 2005 Feb;67(2):513-22. Epub 2004 Nov 3.
PMID: 15525757 [PubMed - indexed for MEDLINE]
22:
Dumbacher JP, Wako A, Derrickson SR, Samuelson A, Spande TF, Daly JW.
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Free in PMCMelyrid beetles (Choresine): a putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds.
Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15857-60. Epub 2004 Nov 1.
PMID: 15520388 [PubMed - indexed for MEDLINE]
23:
Wang SY, Moczydlowski E, Wang G.
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AbstractInactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.
Receptors Channels. 2004;10(3-4):131-8.
PMID: 15512848 [PubMed - indexed for MEDLINE]
24:
Tasso SM, Moon SCh, Bruno-Blanch LE, Estiu GL.
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AbstractCharacterization of the anticonvulsant profile of valpromide derivatives.
Bioorg Med Chem. 2004 Jul 15;12(14):3857-69.
PMID: 15210153 [PubMed - indexed for MEDLINE]
25:
Callaway JK, Castillo-Melendez M, Giardina SF, Krstew EK, Beart PM, Jarrott B.
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AbstractSodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence.
Neuropharmacology. 2004 Jul;47(1):146-55.
PMID: 15165842 [PubMed - indexed for MEDLINE]
26:
Wartenberg HC, Urban BW.
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AbstractSingle sodium channels from human skeletal muscle in planar lipid bilayers: characterization and response to pentobarbital.
J Anesth. 2004;18(2):100-6.
PMID: 15127257 [PubMed - indexed for MEDLINE]
27:
Trudeau S, Deslongchamps P.
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AbstractNovel synthesis of highly functionalized 14-beta-hydroxysteroids related to batrachotoxin and ouabain.
J Org Chem. 2004 Feb 6;69(3):832-8.
PMID: 14750812 [PubMed - indexed for MEDLINE]
28:
Liao C, Zheng J, David LS, Nicholson RA.
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AbstractInhibition of voltage-sensitive sodium channels by the cannabinoid 1 receptor antagonist AM 251 in mammalian brain.
Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):73-8.
PMID: 14748850 [PubMed - indexed for MEDLINE]
29:
Fernandes de Oliveira J, Teixeira CE, Arantes EC, de Nucci G, Antunes E.
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AbstractRelaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway.
Urology. 2003 Sep;62(3):581-8.
PMID: 12946781 [PubMed - indexed for MEDLINE]
30:
Castillo C, Thornhill WB, Zhu J, Recio-Pinto E.
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AbstractThe permeation and activation properties of brain sodium channels change during development.
Brain Res Dev Brain Res. 2003 Aug 12;144(1):99-106.
PMID: 12888221 [PubMed - indexed for MEDLINE]
31:
De Leon L, Ragsdale DS.
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AbstractState-dependent access to the batrachotoxin receptor on the sodium channel.
Neuroreport. 2003 Jul 18;14(10):1353-6.
PMID: 12876472 [PubMed - indexed for MEDLINE]
32:
Hui K, McIntyre D, French RJ.
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Free Full TextConotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel.
J Gen Physiol. 2003 Jul;122(1):63-79.
PMID: 12835471 [PubMed - indexed for MEDLINE]
33:
Nicholson RA, Liao C, Zheng J, David LS, Coyne L, Errington AC, Singh G, Lees G.
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AbstractSodium channel inhibition by anandamide and synthetic cannabimimetics in brain.
Brain Res. 2003 Jul 18;978(1-2):194-204.
PMID: 12834914 [PubMed - indexed for MEDLINE]
34:
Wartenberg HC, Wartenberg JP, Urban BW.
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AbstractPharmacological modification of sodium channels from the human heart atrium in planar lipid bilayers: electrophysiological characterization of responses to batrachotoxin and pentobarbital.
Eur J Anaesthesiol. 2003 May;20(5):354-62.
PMID: 12790206 [PubMed - indexed for MEDLINE]
35:
Wang SY, Wang GK.
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AbstractVoltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins.
Cell Signal. 2003 Feb;15(2):151-9. Review.
PMID: 12464386 [PubMed - indexed for MEDLINE]
36:
Cronin NB, O'Reilly A, Duclohier H, Wallace BA.
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Free Full TextBinding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation.
J Biol Chem. 2003 Mar 21;278(12):10675-82. Epub 2002 Nov 12.
PMID: 12431988 [PubMed - indexed for MEDLINE]
37:
Nicholson GM, Blanche T, Mansfield K, Tran Y.
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AbstractDifferential blockade of neuronal voltage-gated Na(+) and K(+) channels by antidepressant drugs.
Eur J Pharmacol. 2002 Sep 27;452(1):35-48.
PMID: 12323383 [PubMed - indexed for MEDLINE]
38:
Grauert M, Bechtel WD, Weiser T, Stransky W, Nar H, Carter AJ.
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AbstractSynthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.
J Med Chem. 2002 Aug 15;45(17):3755-64.
PMID: 12166948 [PubMed - indexed for MEDLINE]
39:
Flowers A, Onwueme K, Creveling CR, Daly JW.
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AbstractReserpine: interactions with batrachotoxin and brevetoxin sites on voltage-dependent sodium channels.
Cell Mol Neurobiol. 2002 Feb;22(1):1-12.
PMID: 12064513 [PubMed - indexed for MEDLINE]
40:
Castaneda-Castellanos DR, Nikonorov I, Kallen RG, Recio-Pinto E.
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AbstractLidocaine stabilizes the open state of CNS voltage-dependent sodium channels.
Brain Res Mol Brain Res. 2002 Mar 28;99(2):102-13.
PMID: 11978401 [PubMed - indexed for MEDLINE]
41:
Li HL, Hadid D, Ragsdale DS.
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Free Full TextThe batrachotoxin receptor on the voltage-gated sodium channel is guarded by the channel activation gate.
Mol Pharmacol. 2002 Apr;61(4):905-12.
PMID: 11901230 [PubMed - indexed for MEDLINE]
42:
Wright SN.
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Free Full TextComparison of aconitine-modified human heart (hH1) and rat skeletal (mu1) muscle Na+ channels: an important role for external Na+ ions.
J Physiol. 2002 Feb 1;538(Pt 3):759-71.
PMID: 11826163 [PubMed - indexed for MEDLINE]
43:
Wartenberg HC, Wartenberg JP, Urban BW.
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AbstractSingle sodium channels from human ventricular muscle in planar lipid bilayers.
Basic Res Cardiol. 2001 Nov;96(6):645-51.
PMID: 11770084 [PubMed - indexed for MEDLINE]
44:
Leong D, Bloomquist JR, Bempong J, Dybas JA, Kinne LP, Lyga JW, Marek FL, Nicholson RA.
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AbstractInsecticidal arylalkylbenzhydrolpiperidines: novel inhibitors of voltage-sensitive sodium and calcium channels in mammalian brain.
Pest Manag Sci. 2001 Oct;57(10):889-95.
PMID: 11695181 [PubMed - indexed for MEDLINE]
45:
Kurosu M, Kishi Y.
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No AbstractA Novel Example for Optical Resolution of Racemic Ketones Originating from Batrachotoxin Synthesis.
J Org Chem. 1998 Sep 4;63(18):6100-6101. No abstract available.
PMID: 11672234 [PubMed - as supplied by publisher]
46:
Wang SY, Barile M, Wang GK.
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Free Full TextA phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
Mol Pharmacol. 2001 Sep;60(3):620-8.
PMID: 11502895 [PubMed - indexed for MEDLINE]
47:
Marinov BS, Wang GK.
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AbstractRedox properties of local anesthetics: A structural determinant of closed channel blockers in BTX-modified Na+ channels.
Membr Cell Biol. 2001;14(4):553-63.
PMID: 11497109 [PubMed - indexed for MEDLINE]
48:
Yuki T, Yamaoka K, Yakehiro M, Seyama I.
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Free Full TextState-dependent action of grayanotoxin I on Na(+) channels in frog ventricular myocytes.
J Physiol. 2001 Aug 1;534(Pt 3):777-90.
PMID: 11483708 [PubMed - indexed for MEDLINE]
49:
Li WI, Berman FW, Okino T, Yokokawa F, Shioiri T, Gerwick WH, Murray TF.
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Free in PMCAntillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels.
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7599-604.
PMID: 11416227 [PubMed - indexed for MEDLINE]
50:
Bonifacio MJ, Sheridan RD, Parada A, Cunha RA, Patmore L, Soares-da-Silva P.
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AbstractInteraction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine.
Epilepsia. 2001 May;42(5):600-8.
PMID: 11380566 [PubMed - indexed for MEDLINE]
51:
Summers K, Clough ME.
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Free in PMCThe evolution of coloration and toxicity in the poison frog family (Dendrobatidae).
Proc Natl Acad Sci U S A. 2001 May 22;98(11):6227-32. Epub 2001 May 15.
PMID: 11353830 [PubMed - indexed for MEDLINE]
52:
Wartenberg HC, Wartenberg JP, Urban BW.
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AbstractHuman cardiac sodium channels are affected by pentobarbital.
Eur J Anaesthesiol. 2001 May;18(5):306-13.
PMID: 11350473 [PubMed - indexed for MEDLINE]
53:
Wang SY, Barile M, Wang GK.
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Free Full TextDisparate role of Na(+) channel D2-S6 residues in batrachotoxin and local anesthetic action.
Mol Pharmacol. 2001 May;59(5):1100-7.
PMID: 11306693 [PubMed - indexed for MEDLINE]
54:
Bloom KJ, Grivetti LE.
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No AbstractThe mysterious history of partridge poisoning.
J Hist Med Allied Sci. 2001 Jan;56(1):68-76. No abstract available.
PMID: 11236237 [PubMed - indexed for MEDLINE]
55:
Xiao YF, Ke Q, Wang SY, Yang Y, Wang GK, Morgan JP, Leaf A.
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AbstractPoint mutations in alpha-subunit of human cardiac Na+ channels alter Na+ current kinetics.
Biochem Biophys Res Commun. 2001 Feb 16;281(1):45-52.
PMID: 11178958 [PubMed - indexed for MEDLINE]
56:
Wright SN.
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Free Full TextIrreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine.
Mol Pharmacol. 2001 Feb;59(2):183-92.
PMID: 11160852 [PubMed - indexed for MEDLINE]
57:
Vamecq J, Bac P, Herrenknecht C, Maurois P, Delcourt P, Stables JP.
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AbstractSynthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore.
J Med Chem. 2000 Apr 6;43(7):1311-9.
PMID: 10753468 [PubMed - indexed for MEDLINE]
58:
Nicholson RA, Zheng J, Ganellin CR, Verdon B, Lees G.
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AbstractAnesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain.
Anesthesiology. 2001 Jan;94(1):120-8. Erratum in: Anesthesiology 2001 Apr;94(4):723.
PMID: 11135731 [PubMed - indexed for MEDLINE]
59:
Lee SH, Soderlund DM.
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AbstractThe V410M mutation associated with pyrethroid resistance in Heliothis virescens reduces the pyrethroid sensitivity of house fly sodium channels expressed in Xenopus oocytes.
Insect Biochem Mol Biol. 2001 Jan;31(1):19-29.
PMID: 11102831 [PubMed - indexed for MEDLINE]
60:
Weldon PJ.
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Free in PMCAvian chemical defense: toxic birds not of a feather.
Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):12948-9. Review. No abstract available.
PMID: 11087849 [PubMed - indexed for MEDLINE]
61:
Melena J, Chidlow G, Osborne NN.
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AbstractBlockade of voltage-sensitive Na(+) channels by the 5-HT(1A) receptor agonist 8-OH-DPAT: possible significance for neuroprotection.
Eur J Pharmacol. 2000 Oct 20;406(3):319-24.
PMID: 11040337 [PubMed - indexed for MEDLINE]
62:
Dumbacher JP, Spande TF, Daly JW.
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Free in PMCBatrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldi) from New Guinea.
Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):12970-5.
PMID: 11035772 [PubMed - indexed for MEDLINE]
63:
Chao HM, Chidlow G, Melena J, Wood JP, Osborne NN.
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AbstractAn investigation into the potential mechanisms underlying the neuroprotective effect of clonidine in the retina.
Brain Res. 2000 Sep 15;877(1):47-57.
PMID: 10980242 [PubMed - indexed for MEDLINE]
64:
Vladimirov M, Nau C, Mok WM, Strichartz G.
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AbstractPotency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies.
Anesthesiology. 2000 Sep;93(3):744-55.
PMID: 10969308 [PubMed - indexed for MEDLINE]
65:
Wang SY, Nau C, Wang GK.
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Free in PMCResidues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
Biophys J. 2000 Sep;79(3):1379-87.
PMID: 10969000 [PubMed - indexed for MEDLINE]
66:
Chidlow G, Melena J, Osborne NN.
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Free Full TextBetaxolol, a beta(1)-adrenoceptor antagonist, reduces Na(+) influx into cortical synaptosomes by direct interaction with Na(+) channels: comparison with other beta-adrenoceptor antagonists.
Br J Pharmacol. 2000 Jun;130(4):759-66.
PMID: 10864881 [PubMed - indexed for MEDLINE]
67:
Vedantham V, Cannon SC.
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Free in PMCRapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channels.
Biophys J. 2000 Jun;78(6):2943-58.
PMID: 10827974 [PubMed - indexed for MEDLINE]
68:
Wang GK, Quan C, Seaver M, Wang SY.
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AbstractModification of wild-type and batrachotoxin-resistant muscle mu1 Na+ channels by veratridine.
Pflugers Arch. 2000 Apr;439(6):705-13.
PMID: 10784344 [PubMed - indexed for MEDLINE]
69:
Carter AJ, Grauert M, Pschorn U, Bechtel WD, Bartmann-Lindholm C, Qu Y, Scheuer T, Catterall WA, Weiser T.
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Free in PMCPotent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL.
Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4944-9.
PMID: 10781102 [PubMed - indexed for MEDLINE]
70:
Ishii H, Kinoshita E, Kimura T, Yakehiro M, Yamaoka K, Imoto K, Mori Y, Seyama I.
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AbstractPoint-mutations related to the loss of batrachotoxin binding abolish the grayanotoxin effect in Na(+) channel isoforms.
Jpn J Physiol. 1999 Oct;49(5):457-61.
PMID: 10603430 [PubMed - indexed for MEDLINE]
71:
He H, Chen AC, Davey RB, Ivie GW, George JE.
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AbstractIdentification of a point mutation in the para-type sodium channel gene from a pyrethroid-resistant cattle tick.
Biochem Biophys Res Commun. 1999 Aug 11;261(3):558-61.
PMID: 10441465 [PubMed - indexed for MEDLINE]
72:
Nau C, Wang SY, Strichartz GR, Wang GK.
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Free Full TextPoint mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers.
Mol Pharmacol. 1999 Aug;56(2):404-13.
PMID: 10419561 [PubMed - indexed for MEDLINE]
73:
Wang SY, Wang GK.
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Free in PMCBatrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6.
Biophys J. 1999 Jun;76(6):3141-9.
PMID: 10354438 [PubMed - indexed for MEDLINE]
74:
Roman FJ, Lanet S, Hamon J, Brunelle G, Maurin A, Champeroux P, Richard S, Alessandri N, Gola M.
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Free Full TextPharmacological properties of trimebutine and N-monodesmethyltrimebutine.
J Pharmacol Exp Ther. 1999 Jun;289(3):1391-7.
PMID: 10336531 [PubMed - indexed for MEDLINE]
75:
Weiser T, Brenner M, Palluk R, Bechtel WD, Ceci A, Brambilla A, Ensinger HA, Sagrada A, Wienrich M.
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Free Full TextBIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
J Pharmacol Exp Ther. 1999 Jun;289(3):1343-9.
PMID: 10336525 [PubMed - indexed for MEDLINE]
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Shimojo M, Takasugi K, Yamamoto I, Funato H, Mochizuki H, Kohsaka S.
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AbstractNeuroprotective action of a novel compound--M50463--in primary cultured neurons.
Brain Res. 1999 Jan 2;815(1):131-9.
PMID: 9974133 [PubMed - indexed for MEDLINE]
77:
Little MJ, Wilson H, Zappia C, Cestele S, Tyler MI, Martin-Eauclaire MF, Gordon D, Nicholson GM.
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AbstractDelta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels.
FEBS Lett. 1998 Nov 20;439(3):246-52.
PMID: 9845331 [PubMed - indexed for MEDLINE]
78:
Linford NJ, Cantrell AR, Qu Y, Scheuer T, Catterall WA.
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Free in PMCInteraction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel.
Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13947-52.
PMID: 9811906 [PubMed - indexed for MEDLINE]
79:
Little MJ, Zappia C, Gilles N, Connor M, Tyler MI, Martin-Eauclaire MF, Gordon D, Nicholson GM.
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Free Full Textdelta-Atracotoxins from australian funnel-web spiders compete with scorpion alpha-toxin binding but differentially modulate alkaloid toxin activation of voltage-gated sodium channels.
J Biol Chem. 1998 Oct 16;273(42):27076-83.
PMID: 9765223 [PubMed - indexed for MEDLINE]
80:
Benoit E.
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Abstract[Mechanism of action of neurotoxins acting on the inactivation of voltage-gated sodium channels]
C R Seances Soc Biol Fil. 1998;192(3):409-36. Review. French.
PMID: 9759381 [PubMed - indexed for MEDLINE]
81:
Zhou L, Zhang CL, Messing A, Chiu SY.
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Free Full TextTemperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves.
J Neurosci. 1998 Sep 15;18(18):7200-15.
PMID: 9736643 [PubMed - indexed for MEDLINE]
82:
Vamecq J, Lambert D, Poupaert JH, Masereel B, Stables JP.
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AbstractAnticonvulsant activity and interactions with neuronal voltage-dependent sodium channel of analogues of ameltolide.
J Med Chem. 1998 Aug 27;41(18):3307-13.
PMID: 9719582 [PubMed - indexed for MEDLINE]
83:
Friese J, Gleitz J.
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AbstractKavain, dihydrokavain, and dihydromethysticin non-competitively inhibit the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels.
Planta Med. 1998 Jun;64(5):458-9.
PMID: 9690349 [PubMed - indexed for MEDLINE]
84:
Wang GK, Quan C, Wang SY.
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Free Full TextLocal anesthetic block of batrachotoxin-resistant muscle Na+ channels.
Mol Pharmacol. 1998 Aug;54(2):389-96.
PMID: 9687581 [PubMed - indexed for MEDLINE]
85:
Frenkel C, Weckbecker K, Wartenberg HC, Duch DS, Urban BW.
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AbstractBlocking effects of the anaesthetic etomidate on human brain sodium channels.
Neurosci Lett. 1998 Jun 19;249(2-3):131-4.
PMID: 9682834 [PubMed - indexed for MEDLINE]
86:
Ulbricht W.
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AbstractEffects of veratridine on sodium currents and fluxes.
Rev Physiol Biochem Pharmacol. 1998;133:1-54. Review.
PMID: 9600010 [PubMed - indexed for MEDLINE]
87:
Ratnakumari L, Hemmings HC Jr.
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AbstractInhibition of presynaptic sodium channels by halothane.
Anesthesiology. 1998 Apr;88(4):1043-54.
PMID: 9579514 [PubMed - indexed for MEDLINE]
88:
Wang SY, Wang GK.
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Free in PMCPoint mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2653-8.
PMID: 9482942 [PubMed - indexed for MEDLINE]
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Gutser UT, Friese J, Heubach JF, Matthiesen T, Selve N, Wilffert B, Gleitz J.
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AbstractMode of antinociceptive and toxic action of alkaloids of Aconitum spec..
Naunyn Schmiedebergs Arch Pharmacol. 1998 Jan;357(1):39-48.
PMID: 9459571 [PubMed - indexed for MEDLINE]
90:
Hann RM, Pagan OR, Gregory LM, Jacome T, Eterovic VA.
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AbstractThe 9-arginine residue of alpha-conotoxin GI is responsible for its selective high affinity for the alphagamma agonist site on the electric organ acetylcholine receptor.
Biochemistry. 1997 Jul 22;36(29):9051-6.
PMID: 9220994 [PubMed - indexed for MEDLINE]
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Frenkel C, Gerhard A, Wartenberg HC, Rehberg B, Urban BW.
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AbstractNo evidence for specific opioid effects on batrachotoxin-modified sodium channels from human brain synaptosomes.
Neurosci Lett. 1997 Jun 20;229(1):41-4.
PMID: 9224797 [PubMed - indexed for MEDLINE]
92:
Shimidzu T, Itoh Y, Tatsumi S, Hayashi S, Ukai Y, Yoshikuni Y, Kimura K.
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AbstractBlockade of voltage-sensitive sodium channels by NS-7, a novel neuroprotective compound, in the rat brain.
Naunyn Schmiedebergs Arch Pharmacol. 1997 May;355(5):601-8.
PMID: 9151299 [PubMed - indexed for MEDLINE]
93:
Kang JX, Li Y, Leaf A.
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Free in PMCRegulation of sodium channel gene expression by class I antiarrhythmic drugs and n - 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes.
Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2724-8.
PMID: 9122264 [PubMed - indexed for MEDLINE]
94:
Badio B, Garraffo HM, Padgett WL, Greig NH, Daly JW.
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AbstractPseudophrynaminol: a potent noncompetitive blocker of nicotinic receptor-channels.
Biochem Pharmacol. 1997 Mar 7;53(5):671-6.
PMID: 9113086 [PubMed - indexed for MEDLINE]
95:
Brown ML, Brown GB, Brouillette WJ.
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AbstractEffects of log P and phenyl ring conformation on the binding of 5-phenylhydantoins to the voltage-dependent sodium channel.
J Med Chem. 1997 Feb 14;40(4):602-7.
PMID: 9046351 [PubMed - indexed for MEDLINE]
96:
Paillart C, Carlier E, Guedin D, Dargent B, Couraud F.
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Free Full TextDirect block of voltage-sensitive sodium channels by genistein, a tyrosine kinase inhibitor.
J Pharmacol Exp Ther. 1997 Feb;280(2):521-6.
PMID: 9023259 [PubMed - indexed for MEDLINE]
97:
Sauviat MP.
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Abstract[Effect of neurotoxins on the electrical activity and contraction of the heart muscle]
C R Seances Soc Biol Fil. 1997;191(3):451-71. Review. French.
PMID: 9295968 [PubMed - indexed for MEDLINE]
98:
Ratnakumari L, Hemmings HC Jr.
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AbstractInhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes.
Br J Pharmacol. 1996 Dec;119(7):1498-504.
PMID: 8968561 [PubMed - indexed for MEDLINE]
99:
Shichor I, Fainzilber M, Pelhate M, Malecot CO, Zlotkin E, Gordon D.
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AbstractInteractions of delta-conotoxins with alkaloid neurotoxins reveal differences between the silent and effective binding sites on voltage-sensitive sodium channels.
J Neurochem. 1996 Dec;67(6):2451-60.
PMID: 8931478 [PubMed - indexed for MEDLINE]
100:
Gleitz J, Friese J, Beile A, Ameri A, Peters T.
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AbstractAnticonvulsive action of (+/-)-kavain estimated from its properties on stimulated synaptosomes and Na+ channel receptor sites.
Eur J Pharmacol. 1996 Nov 7;315(1):89-97.
PMID: 8960869 [PubMed - indexed for MEDLINE]