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Search batrachotoxin



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Items 1 -100 of 100

1:
Tikhonov DB.

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Abstract[Mechanisms of action of voltage-gated sodium channel ligands]
Ross Fiziol Zh Im I M Sechenova. 2007 May;93(5):531-43. Russian.
PMID: 17650621 [PubMed - indexed for MEDLINE]
2:
Duan Y, Zheng J, Nicholson RA.

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AbstractVanilloid (subtype 1) receptor-modulatory drugs inhibit [3H]batrachotoxinin-A 20-alpha-benzoate binding to Na+ channels.
Basic Clin Pharmacol Toxicol. 2007 Feb;100(2):91-5.
PMID: 17244257 [PubMed - indexed for MEDLINE]
3:
Liberatore AM, Schulz J, Favre-Guilmard C, Pommier J, Lannoy J, Pawlowski E, Barthelemy MA, Huchet M, Auguet M, Chabrier PE, Bigg D.

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AbstractButyl 2-(4-[1.1'-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain.
Bioorg Med Chem Lett. 2007 Mar 15;17(6):1746-9. Epub 2006 Dec 22.
PMID: 17234409 [PubMed - indexed for MEDLINE]
4:
Wang SY, Tikhonov DB, Zhorov BS, Mitchell J, Wang GK.

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AbstractSerine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel.
Pflugers Arch. 2007 May;454(2):277-87. Epub 2007 Jan 5.
PMID: 17205354 [PubMed - indexed for MEDLINE]
5:
Wang SY, Mitchell J, Wang GK.

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AbstractPreferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel.
Pain. 2007 Jan;127(1-2):73-83. Epub 2006 Sep 7.
PMID: 16962240 [PubMed - indexed for MEDLINE]
6:
Errington AC, Coyne L, Stohr T, Selve N, Lees G.

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AbstractSeeking a mechanism of action for the novel anticonvulsant lacosamide.
Neuropharmacology. 2006 Jun;50(8):1016-29. Epub 2006 Apr 18.
PMID: 16620882 [PubMed - indexed for MEDLINE]
7:
Wang GK, Edrich T, Wang SY.

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Free Full TextTime-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
J Gen Physiol. 2006 Mar;127(3):277-89.
PMID: 16505148 [PubMed - indexed for MEDLINE]
8:
Popa MO, Lerche H.

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Free Full TextCu2+ (1,10 phenanthroline)3 is an open-channel blocker of the human skeletal muscle sodium channel.
Br J Pharmacol. 2006 Apr;147(7):808-14.
PMID: 16432503 [PubMed - indexed for MEDLINE]
9:
Duan Y, Zheng J, Law V, Nicholson R.

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AbstractNatural products from ginseng inhibit [3H]batrachotoxinin A 20-alpha-benzoate binding to Na+ channels in mammalian brain.
Eur J Pharmacol. 2006 Jan 13;530(1-2):9-14. Epub 2005 Dec 15.
PMID: 16359658 [PubMed - indexed for MEDLINE]
10:
Wang SY, Mitchell J, Tikhonov DB, Zhorov BS, Wang GK.

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Free Full TextHow batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis.
Mol Pharmacol. 2006 Mar;69(3):788-95. Epub 2005 Dec 14.
PMID: 16354762 [PubMed - indexed for MEDLINE]
11:
Riddall DR, Leach MJ, Garthwaite J.

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Free Full TextA novel drug binding site on voltage-gated sodium channels in rat brain.
Mol Pharmacol. 2006 Jan;69(1):278-87. Epub 2005 Oct 11.
PMID: 16219909 [PubMed - indexed for MEDLINE]
12:
Tikhonov DB, Zhorov BS.

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AbstractSodium channel activators: model of binding inside the pore and a possible mechanism of action.
FEBS Lett. 2005 Aug 15;579(20):4207-12.
PMID: 16083886 [PubMed - indexed for MEDLINE]
13:
LePage KT, Goeger D, Yokokawa F, Asano T, Shioiri T, Gerwick WH, Murray TF.

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AbstractThe neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons.
Toxicol Lett. 2005 Aug 14;158(2):133-9. Epub 2005 Apr 9.
PMID: 16039402 [PubMed - indexed for MEDLINE]
14:
Berra-Romani R, Blaustein MP, Matteson DR.

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Free Full TextTTX-sensitive voltage-gated Na+ channels are expressed in mesenteric artery smooth muscle cells.
Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H137-45.
PMID: 15961372 [PubMed - indexed for MEDLINE]
15:
Fitch RW, Daly JW.

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AbstractPhosphorimaging detection and quantitation for isotopic ion flux assays.
Anal Biochem. 2005 Jul 15;342(2):260-70.
PMID: 15950910 [PubMed - indexed for MEDLINE]
16:
Cronin NB, O'Reilly A, Duclohier H, Wallace BA.

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AbstractEffects of deglycosylation of sodium channels on their structure and function.
Biochemistry. 2005 Jan 18;44(2):441-9.
PMID: 15641768 [PubMed - indexed for MEDLINE]
17:
Nau C, Wang GK.

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AbstractInteractions of local anesthetics with voltage-gated Na+ channels.
J Membr Biol. 2004 Sep 1;201(1):1-8. Review.
PMID: 15635807 [PubMed - indexed for MEDLINE]
18:
Chevalier E, Petoux F, Chovet M, Langlois A.

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AbstractBeneficial effect of trimebutine and N-monodesmethyl trimebutine on trinitrobenzene sulfonic acid-induced colitis in rats.
Life Sci. 2004 Dec 3;76(3):319-29.
PMID: 15531383 [PubMed - indexed for MEDLINE]
19:
Kong KH, Chen Y, Ma X, Chui WK, Lam Y.

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AbstractTraceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels.
J Comb Chem. 2004 Nov-Dec;6(6):928-33.
PMID: 15530120 [PubMed - indexed for MEDLINE]
20:
Bosmans F, Maertens C, Verdonck F, Tytgat J.

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AbstractThe poison Dart frog's batrachotoxin modulates Nav1.8.
FEBS Lett. 2004 Nov 5;577(1-2):245-8.
PMID: 15527793 [PubMed - indexed for MEDLINE]
21:
Tan J, Liu Z, Wang R, Huang ZY, Chen AC, Gurevitz M, Dong K.

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Free Full TextIdentification of amino acid residues in the insect sodium channel critical for pyrethroid binding.
Mol Pharmacol. 2005 Feb;67(2):513-22. Epub 2004 Nov 3.
PMID: 15525757 [PubMed - indexed for MEDLINE]
22:
Dumbacher JP, Wako A, Derrickson SR, Samuelson A, Spande TF, Daly JW.

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Free in PMCMelyrid beetles (Choresine): a putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds.
Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15857-60. Epub 2004 Nov 1.
PMID: 15520388 [PubMed - indexed for MEDLINE]
23:
Wang SY, Moczydlowski E, Wang G.

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AbstractInactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.
Receptors Channels. 2004;10(3-4):131-8.
PMID: 15512848 [PubMed - indexed for MEDLINE]
24:
Tasso SM, Moon SCh, Bruno-Blanch LE, Estiu GL.

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AbstractCharacterization of the anticonvulsant profile of valpromide derivatives.
Bioorg Med Chem. 2004 Jul 15;12(14):3857-69.
PMID: 15210153 [PubMed - indexed for MEDLINE]
25:
Callaway JK, Castillo-Melendez M, Giardina SF, Krstew EK, Beart PM, Jarrott B.

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AbstractSodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence.
Neuropharmacology. 2004 Jul;47(1):146-55.
PMID: 15165842 [PubMed - indexed for MEDLINE]
26:
Wartenberg HC, Urban BW.

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AbstractSingle sodium channels from human skeletal muscle in planar lipid bilayers: characterization and response to pentobarbital.
J Anesth. 2004;18(2):100-6.
PMID: 15127257 [PubMed - indexed for MEDLINE]
27:
Trudeau S, Deslongchamps P.

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AbstractNovel synthesis of highly functionalized 14-beta-hydroxysteroids related to batrachotoxin and ouabain.
J Org Chem. 2004 Feb 6;69(3):832-8.
PMID: 14750812 [PubMed - indexed for MEDLINE]
28:
Liao C, Zheng J, David LS, Nicholson RA.

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AbstractInhibition of voltage-sensitive sodium channels by the cannabinoid 1 receptor antagonist AM 251 in mammalian brain.
Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):73-8.
PMID: 14748850 [PubMed - indexed for MEDLINE]
29:
Fernandes de Oliveira J, Teixeira CE, Arantes EC, de Nucci G, Antunes E.

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AbstractRelaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway.
Urology. 2003 Sep;62(3):581-8.
PMID: 12946781 [PubMed - indexed for MEDLINE]
30:
Castillo C, Thornhill WB, Zhu J, Recio-Pinto E.

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AbstractThe permeation and activation properties of brain sodium channels change during development.
Brain Res Dev Brain Res. 2003 Aug 12;144(1):99-106.
PMID: 12888221 [PubMed - indexed for MEDLINE]
31:
De Leon L, Ragsdale DS.

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AbstractState-dependent access to the batrachotoxin receptor on the sodium channel.
Neuroreport. 2003 Jul 18;14(10):1353-6.
PMID: 12876472 [PubMed - indexed for MEDLINE]
32:
Hui K, McIntyre D, French RJ.

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Free Full TextConotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel.
J Gen Physiol. 2003 Jul;122(1):63-79.
PMID: 12835471 [PubMed - indexed for MEDLINE]
33:
Nicholson RA, Liao C, Zheng J, David LS, Coyne L, Errington AC, Singh G, Lees G.

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AbstractSodium channel inhibition by anandamide and synthetic cannabimimetics in brain.
Brain Res. 2003 Jul 18;978(1-2):194-204.
PMID: 12834914 [PubMed - indexed for MEDLINE]
34:
Wartenberg HC, Wartenberg JP, Urban BW.

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AbstractPharmacological modification of sodium channels from the human heart atrium in planar lipid bilayers: electrophysiological characterization of responses to batrachotoxin and pentobarbital.
Eur J Anaesthesiol. 2003 May;20(5):354-62.
PMID: 12790206 [PubMed - indexed for MEDLINE]
35:
Wang SY, Wang GK.

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AbstractVoltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins.
Cell Signal. 2003 Feb;15(2):151-9. Review.
PMID: 12464386 [PubMed - indexed for MEDLINE]
36:
Cronin NB, O'Reilly A, Duclohier H, Wallace BA.

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Free Full TextBinding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation.
J Biol Chem. 2003 Mar 21;278(12):10675-82. Epub 2002 Nov 12.
PMID: 12431988 [PubMed - indexed for MEDLINE]
37:
Nicholson GM, Blanche T, Mansfield K, Tran Y.

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AbstractDifferential blockade of neuronal voltage-gated Na(+) and K(+) channels by antidepressant drugs.
Eur J Pharmacol. 2002 Sep 27;452(1):35-48.
PMID: 12323383 [PubMed - indexed for MEDLINE]
38:
Grauert M, Bechtel WD, Weiser T, Stransky W, Nar H, Carter AJ.

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AbstractSynthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.
J Med Chem. 2002 Aug 15;45(17):3755-64.
PMID: 12166948 [PubMed - indexed for MEDLINE]
39:
Flowers A, Onwueme K, Creveling CR, Daly JW.

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AbstractReserpine: interactions with batrachotoxin and brevetoxin sites on voltage-dependent sodium channels.
Cell Mol Neurobiol. 2002 Feb;22(1):1-12.
PMID: 12064513 [PubMed - indexed for MEDLINE]
40:
Castaneda-Castellanos DR, Nikonorov I, Kallen RG, Recio-Pinto E.

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AbstractLidocaine stabilizes the open state of CNS voltage-dependent sodium channels.
Brain Res Mol Brain Res. 2002 Mar 28;99(2):102-13.
PMID: 11978401 [PubMed - indexed for MEDLINE]
41:
Li HL, Hadid D, Ragsdale DS.

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Free Full TextThe batrachotoxin receptor on the voltage-gated sodium channel is guarded by the channel activation gate.
Mol Pharmacol. 2002 Apr;61(4):905-12.
PMID: 11901230 [PubMed - indexed for MEDLINE]
42:
Wright SN.

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Free Full TextComparison of aconitine-modified human heart (hH1) and rat skeletal (mu1) muscle Na+ channels: an important role for external Na+ ions.
J Physiol. 2002 Feb 1;538(Pt 3):759-71.
PMID: 11826163 [PubMed - indexed for MEDLINE]
43:
Wartenberg HC, Wartenberg JP, Urban BW.

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AbstractSingle sodium channels from human ventricular muscle in planar lipid bilayers.
Basic Res Cardiol. 2001 Nov;96(6):645-51.
PMID: 11770084 [PubMed - indexed for MEDLINE]
44:
Leong D, Bloomquist JR, Bempong J, Dybas JA, Kinne LP, Lyga JW, Marek FL, Nicholson RA.

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AbstractInsecticidal arylalkylbenzhydrolpiperidines: novel inhibitors of voltage-sensitive sodium and calcium channels in mammalian brain.
Pest Manag Sci. 2001 Oct;57(10):889-95.
PMID: 11695181 [PubMed - indexed for MEDLINE]
45:
Kurosu M, Kishi Y.

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No AbstractA Novel Example for Optical Resolution of Racemic Ketones Originating from Batrachotoxin Synthesis.
J Org Chem. 1998 Sep 4;63(18):6100-6101. No abstract available.
PMID: 11672234 [PubMed - as supplied by publisher]
46:
Wang SY, Barile M, Wang GK.

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Free Full TextA phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
Mol Pharmacol. 2001 Sep;60(3):620-8.
PMID: 11502895 [PubMed - indexed for MEDLINE]
47:
Marinov BS, Wang GK.

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