SARAFOTOXIN B
Product ID L8129-500UG 
Name SARAFOTOXIN B 
Molecular formula C110H159N27O34S5
Description
A 21 amino-acids peptide with 2 disulfide bridges , synthetic, initially isolated from the venom of the Israeli mole viper Atractaspis engaddensis.
Biological activity

Vasoconstrictor peptide; non-selective endothelin receptor agonist. Causes cardiac arrest probably as a result of coronary vasospasm (By similarity). Displays high agonistic activities towards endothelin-2 receptor (EDNRB) (displays affinity in the picomolar range) and endothelin-1 receptor (EDNRA) (lower affinities).

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 Unité(s) 90.00

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5 Unité(s) 360.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8129-500UG : unit price : free of charge
 Chemical and Physical Properties
Product code L8129-500UG  Molecular weight 2564 Da
Product name SARAFOTOXIN B  Physical form White lyophilized solid
CAS No. 116303-65-2 Melting point
RTECS NA Solubility water, 20% acetonitrile
UNIPROT P13208 Optical Activity
PubChem SID    
PubChem CID 131845706    
Purity > 98 %    
Toxicity(LD50) No Data    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable at room temperature, store preferably at 4°C


 
Savety Recommandations  
 Bibliographic References
Product code L8129-500UG 
Product name SARAFOTOXIN B 

- 1. Aimoto et al (1990) Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges. Biochem.Int. ;
2. Bax et al (1994) Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br.J.Pharmacol. ;
3. Devadason and Henry (1997) Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br.J.Pharmacol.
 Links
Product code L8129-500UG 
Product name SARAFOTOXIN B 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
UNIPROT
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