CONVOLVINE
Product ID L6087 
Name CONVOLVINE 
Molecular formula C16H21NO4
Description

It is an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves. It lowers arterial pressure and acts as a vasodilator.


Tropane alkaloid , from plants of the Convolvulaceae family.
Biological activity

A 0.125 % solution blocks the sensitive nerve endings in frog skin and extends the latency of the reflex response to a painful stimulus. The effect, developing gradually, reaches a maximum 55-60 minutes after application and lasts up to 2 hours. Convolvine (1/1000 to 1/3000) inhibits cardiac activity, dilates the vessels from isolated ear of rabbit at 3 mg/kg and lowers the arterial pressure in decerebrated cats.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

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100 mg 416.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6087 : unit price : free of charge
 Chemical and Physical Properties
Product code L6087  Molecular weight 291.34 g/mol
Product name CONVOLVINE  Physical form
CAS No. 537-30-4 Melting point 114-115 °C
RTECS Solubility In acetone, ethanol, methanol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 279064    
Purity 97 % (TLC, mass spectrometry)    
Toxicity(LD50) SCU-MUS LD50: 15-20 mg/kg    
Chemical Name 8-azabicyclo[3.2.1]octan-3-yl 3,4-dimethoxybenzoate    
Storage & Reconstitution
Recommandations

Store at +4°C, in dark place.
Solution for use : 0.1 - 1 %.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6087 
Product name CONVOLVINE 

- Oreckov et al. Khim. Pharm. Industr. (1933) (Russian). 1:52
- Oreckov et al. Journ. Org. Chem. (1937) (Russian). 7:646
 Links
Product code L6087 
Product name CONVOLVINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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