L6257 - HARMIN HCl
(Syn. : Banisterine)
(Syn. : Banisterine)
HARMIN HCl | Product ID | L6257 |
| Name | HARMIN HCl |
| Molecular formula | C13H12N2O.HCl |
| Description |
It is a potent anti-cancer in glioblastoma cells Harmala alkaloid , obtained from Harmalin, extracted from Peganum harmala seeds. |
| Biological activity |
It decreased cell viability by inducing apoptosis and inhibiting Akt phosphorylation in glioblastoma cells. It also has ability to inhibit self-renewal and promote differentiation of glioblastoma stem like cells. It especially inhibits neurosphere formation of human primary glioblastoma stem like cells. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 104.00 | ||
| 100 mg | 416.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6257 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6257 | Molecular weight | 248.71 g/mol |
| Product name | HARMIN HCl | Physical form | Off-white to pale green powder |
| CAS No. | 343-27-1 | Melting point | 265-270 °C |
| RTECS | MG9450000 | Solubility | In water (13.66 mg/L at 25 °C) |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 5359389 | ||
| Purity | 95 % | ||
| Toxicity(LD50) | IVN-MUS LD50: 38 mg/kg | ||
| Chemical Name | 7-Methoxy-1-methyl-9h-pyrido[3,4-b]indole hydrochloride | ||
| Storage & Reconstitution Recommandations |
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| Savety Recommandations | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use |
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Bibliographic References
| Product code | L6257 |
| Product name | HARMIN HCl |
- Liu H, Han D, Liu Y, Hou X, Wu J, Li H, Yang J, Shen C, Yang G, Fu C, Li X, Che H, Ai J, Zhao S. Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma. J Neurooncol. 2013 Mar;112(1):39-48
- Ferretti V, Gilli P, Borea PA. Structural features controlling the binding of beta-carbolines to the benzodiazepine receptor. Acta Crystallogr B. 2004 Aug;60(Pt 4):481-9
Links
| Product code | L6257 |
| Product name | HARMIN HCl |
| External Links |
PubMed
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