NOTEXIN
Product ID L8104 
Name NOTEXIN 
Molecular formula Np Fraction: C591H878N164O175S16
Ns Fraction: C591H878N166O175S16
Description

It is a toxic presynaptic phospholipase A2 (PLA2) with potent myotoxic activity.

Contains:

- Notexin Np (~60%)
- Notechis Ns (33%), a minor natural variant with K replaced by R in 16


119-amino acid protein with 7 disulfite bonds , from Notechis scutatus snake venom.
Biological activity

Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic activities.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 100ug 180.00

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5 x 100ug 720.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8104 : unit price : free of charge
 Chemical and Physical Properties
Product code L8104  Molecular weight 13574 Da
Product name NOTEXIN  Physical form
CAS No. 37223-96-4 Melting point
RTECS RD3800000 Solubility Well in water and saline
UNIPROT P00608;P00609 Optical Activity
PubChem SID 134222164    
PubChem CID    
Purity > 93 % (HPLC)    
Toxicity(LD50) IVN-MUS LD50: 25 µg/kg    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in freeze-dried state.
In solution, keep at -20 °C.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8104 
Product name NOTEXIN 

- Karlsson et al. Toxicon (1972). 10:405-413
- Mollier et al. Eur. J. Biochem. (1989). 185:263-270
- Halpert et al., J. Biol. Chem. (1975). 250:6990-6997
- Chwetzoff et al., FEBS Letters (1990). 161(2):226-230
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