L8435-100UG - HUWENTOXIN-XVI
(Syn. : HwTx-XVI, U10-theraphotoxin-Hs1a)
(Syn. : HwTx-XVI, U10-theraphotoxin-Hs1a)
HUWENTOXIN-XVI | Product ID | L8435-100UG |
| Name | HUWENTOXIN-XVI |
| Molecular formula | C196H292N50O56S6 |
| Description |
A 39 amino-acids peptide with 3 disulfide bridges , synthetic, initially isolated from the venom of the Chinese gold earth tiger spider Ornithoctonus huwena, also known as Cyriopagopus schmidti, Haplopelma schmidti, Haplopelma huwenum. |
| Biological activity | HWTX-XVIa9 is a potent blocker of HVA N-type calcium channels with an IC50 value of 60 nM in rat DRG. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 170.00 | ||
| 5 Unité(s) | 680.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8435-100UG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8435-100UG | Molecular weight | 4437.2 Da |
| Product name | HUWENTOXIN-XVI | Physical form | White lyophilized solid |
| CAS No. | 1600543-88-1 | Melting point | |
| RTECS | NA | Solubility | water and saline buffer |
| UNIPROT | B3FIP5 | Optical Activity | |
| PubChem SID | |||
| PubChem CID | 90489025 | ||
| Purity | > 98 % | ||
| Toxicity(LD50) | No Data | ||
| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable at room temperature, store preferably at 4°C |
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| Savety Recommandations | |||
Bibliographic References
| Product code | L8435-100UG |
| Product name | HUWENTOXIN-XVI |
- 1. Deng M., et al. (2014) Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena. Neuropharmacol. ;
2. Jiang L., Peng L., Chen J., Zhang Y., Xiong X., Liang S. (2008) : Molecular diversification based on analysis of expressed sequence tags from the venom glands of the Chinese bird spider Ornithoctonus huwena. Toxicon 51:1479-1489.
Links
| Product code | L8435-100UG |
| Product name | HUWENTOXIN-XVI |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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PubChem CID
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 UNIPROT |
