LATROINSECTOTOXIN (alpha-)
Product ID L8409 
Name LATROINSECTOTOXIN (alpha-) 
Molecular formula C5806H9215N1577O1745S27
Description
A 1160 amino-acids peptide , natural, purified from Latrodectus (mactans) tredecimguttatus spider venom glands.
Biological activity

α-latroinsectotoxin-Lt1a (Alpha-LIT) binds with high affinity to insects presynaptic membranes. It stimulates neurotransmitter release from nerve endings, increases intracellular Ca2+ concentration; the biological activity on nerve endings occurs at 10-10-10-9 M.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 50µg 118.00

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5 x 50µg 472.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8409 : unit price : free of charge
 Chemical and Physical Properties
Product code L8409  Molecular weight 129896.19 Da
Product name LATROINSECTOTOXIN (alpha-)  Physical form White lyophilized solid
CAS No. 130810-27-4 Melting point
RTECS Solubility Aqueous buffers, pH range 6.5-8.5.
UNIPROT Q02989 Optical Activity
PubChem SID    
PubChem CID    
Purity >97 %    
Toxicity(LD50) No Data    
Chemical Name    
Storage & Reconstitution
Recommandations

Can be stored at 4 °C in presence of sodium azide up to 0.5 mg/ml during one month without any loss of activity or protein aggregation; a small amount of the lyophilized product cannot be dissolved; repeating thawings and freezings causes a partial loss o


 
Savety Recommandations  
 Bibliographic References
Product code L8409 
Product name LATROINSECTOTOXIN (alpha-) 

- Regarding the physiochemical characteristics:
1. Krasnoperov et al., Bioorg. Khimiya 16:1138-1140 (1990) (Russian).
2. Kovalevskaya et al., Bioorg. Khimiya 16(8):1013-1017 (1990) (Russian).
3. Krasnoperov et al., J. Natural Toxins 1:17-23 (1992).
4. Kiyatkin et al., Eur. J. Biochem. 213:121-127 (1993).
Regarding the biological activity:
1. Kovalevskaya et al., Bioorg. Khimiya 16(8):1013-1017 (1990) (Russian).
2. Magazanik et al., Neuroscience 46:181-188 (1992).
 Links
Product code L8409 
Product name LATROINSECTOTOXIN (alpha-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
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