IMPERIALINE (3-alpha-Chloro-)
Product ID L6032 
Name IMPERIALINE (3-alpha-Chloro-) 
Molecular formula C27H42CINO2

It is a potent long-acting selective M2 muscarinic receptor antagonist, with a strong activity on the brain.

Cervane alkaloid , derivative of Imperialine from the plant Petilium eduardi
Biological activity

3-alpha-Chloro-Imperialine, a long-acting cholinoblocker of M2 receptors, blocks M2 receptors in the heart at 5 μg/kg (i.v.) and the action develops gradually. 3-alpha-Chloro-Imperialine's activity is more than 10 times higher than that of Imperialine and is specially high in the brain.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 1mg 162.00

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5 x 1mg 648.00

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5 mg 648.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6032 : unit price : free of charge
 Chemical and Physical Properties
Product code L6032  Molecular weight 448.08 g/mol
Product name IMPERIALINE (3-alpha-Chloro-)  Physical form
CAS No. 153720-48-0 Melting point 215-220 °C
RTECS Solubility In chloroform
Not well in acetone, methanol, ethanol, water
UNIPROT Optical Activity
PubChem SID    
PubChem CID 98047543    
Purity 97%    
Toxicity(LD50) IVN-MUS LD50: 52 mg/kg    
Chemical Name Cevan-6-one,3-chloro-20-hydroxy-, (3alpha,5alpha,17beta)- (9CI)    
Storage & Reconstitution

Store at +4°C, in dark place.

Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 Bibliographic References
Product code L6032 
Product name IMPERIALINE (3-alpha-Chloro-) 

- Eglen et al., "Characterisation of the interaction of the cervane alkaloid, imperialine, at Muscarinic receptors in vitro." Naunyn-Schmiedebergs Arch. Pharmacol. (1992) 346:144-151
- on 3-b-Bromo-Imperialine: Mirzaev, unbublished results.
Product code L6032 
Product name IMPERIALINE (3-alpha-Chloro-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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