COBRATOXIN (Alpha-)
Product ID L8114 
Name COBRATOXIN (Alpha-) 
Molecular formula
Description

Alpha-Cobratoxin is a long chain postsynaptic neurotoxin, antagonist of nicotinic receptor with a high affinity.


A 71-amino acid polypeptide with 5 disulfide Bonds , purified from Naja kaouthia snake venom.
Biological activity

Alpha-Cobratoxin is a nicotinic cholinoreceptor antagonist: Kd = 55 pM, homologue of postsynaptically acting toxins.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 1mg 140.00

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5 x 1mg 560.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8114 : unit price : free of charge
 Chemical and Physical Properties
Product code L8114  Molecular weight 7,820 Da
Product name COBRATOXIN (Alpha-)  Physical form White solid
CAS No. 69344-74-7 Melting point
RTECS Solubility Well in water and saline
UNIPROT P01391 Optical Activity No optical Activity
PubChem SID    
PubChem CID 91898464    
Purity > 99% (HPLC)    
Toxicity(LD50) IVN-MUS LD100: 100 µg/kg    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in dry state.
Store in a dark place. Keep the solution at -20 °C.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8114 
Product name COBRATOXIN (Alpha-) 

- Ishikawa Y. et al., Toxicon (1977). 15:477-488
- Charpentier I. et al., J. of Molecular Recognition (1990). 3:74-81
- Faure G. et al., Biochemistry (1983). 22:2068-2076
- Karlsson E. et al.,"Isolation of the principal neurotoxins of Naja naja subspecies from the asian mainland." Toxicon (1972). 10:217-225
- Walkinshaw M.D. et al., Proc. Natl. Acad. Sci. USA (1980). 77:2400-2404
- Betzel C. et al., J. Biol. Chem. (1991). 266:21530-21536
 Links
Product code L8114 
Product name COBRATOXIN (Alpha-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
UNIPROT
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