L8114-1MG - COBRATOXIN (Alpha-)
(Syn. : Alpha-Elapitoxin-Nk2a, Neurotoxin III, Long neurotoxin 1)
(Syn. : Alpha-Elapitoxin-Nk2a, Neurotoxin III, Long neurotoxin 1)
COBRATOXIN (Alpha-) | Product ID | L8114-1MG |
| Name | COBRATOXIN (Alpha-) |
| Molecular formula | |
| Description |
Alpha-Cobratoxin is a long chain postsynaptic neurotoxin, antagonist of nicotinic receptor with a high affinity. A 71-amino acid polypeptide with 5 disulfide Bonds , purified from Naja kaouthia snake venom. |
| Biological activity | Alpha-Cobratoxin is a nicotinic cholinoreceptor antagonist: Kd = 55 pM, homologue of postsynaptically acting toxins. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 155.00 | ||
| 5 Unité(s) | 620.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8114-1MG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8114-1MG | Molecular weight | 7,820 Da |
| Product name | COBRATOXIN (Alpha-) | Physical form | White solid |
| CAS No. | 69344-74-7 | Melting point | |
| RTECS | Solubility | Well in water and saline | |
| UNIPROT | P01391 | Optical Activity | No optical Activity |
| PubChem SID | |||
| PubChem CID | 91898464 | ||
| Purity | > 99% (HPLC) | ||
| Toxicity(LD50) | IVN-MUS LD100: 100 õg/kg | ||
| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable in dry state. |
||
| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
||
Bibliographic References
| Product code | L8114-1MG |
| Product name | COBRATOXIN (Alpha-) |
- Ishikawa Y. et al., Toxicon (1977). 15:477-488
- Charpentier I. et al., J. of Molecular Recognition (1990). 3:74-81
- Faure G. et al., Biochemistry (1983). 22:2068-2076
- Karlsson E. et al.,"Isolation of the principal neurotoxins of Naja naja subspecies from the asian mainland." Toxicon (1972). 10:217-225
- Walkinshaw M.D. et al., Proc. Natl. Acad. Sci. USA (1980). 77:2400-2404
- Betzel C. et al., J. Biol. Chem. (1991). 266:21530-21536
Links
| Product code | L8114-1MG |
| Product name | COBRATOXIN (Alpha-) |
| External Links |
PubMed
|
|
Biomedical Citations From PubMed
|
|
|
Toxicology Citations From PubMed
|
|
|
PubChem CID
|
|
 UNIPROT |
