AUSTRICINE | Product ID | L6055 |
| Name | AUSTRICINE |
| Molecular formula | C15H18O4.H2O |
| Description |
It is a hypolipidemic, antiatherosclerotic, anti-inflammatory agent, with angioprotective and hepatoprotective activity. It has also antiulcerous property. Sesquiterpene lactone , from plants of the Compositae family. |
| Biological activity | At 1 mg/kg during 90 days, given with cholesterol, the preparation decreases the area of atherosclerotic damage in aorta, the cholesterol content in this area, the thickness and size of the atherosclerotic plaque. The preparation decreases the aorta and microvessels permeability for high molecular albumine-blue Evans complex, which is increased by feeding with cholesterol or administration of bradykine or ovalbumine. All major lipid classes content in blood serum and liver is decreased after administration of Austricine. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 100 mg | 112.00 | ||
| 500 mg | 448.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6055 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6055 | Molecular weight | 280.32 g/mol |
| Product name | AUSTRICINE | Physical form | Powder |
| CAS No. | 10180-88-8 | Melting point | Melts slightly at 123-125 °C, then hardens and melts at 149-151 °C (alcohol) |
| RTECS | Solubility | In acetone, ethylacetate, dimethylformamide, DMSO Not in water |
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| UNIPROT | Optical Activity | [alpha]D25 + 28 (c 1.1 chloroform) | |
| PubChem SID | 447061 | ||
| PubChem CID | 25102721 | ||
| Purity | 98 % (TLC, mass spectrometry) | ||
| Toxicity(LD50) | ORL-MUS LD50: 5 g/kg | ||
| Chemical Name | (3S,3aR,4S,9aS,9bR)-4-hydroxy-3,6,9-trimethyl-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione;hydrate | ||
| Storage & Reconstitution Recommandations |
Store at +4°C, in dark place. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6055 |
| Product name | AUSTRICINE |
- Rybalko, J. Gen. Chem. (1963) (Russian). 33(8):2734
- Syrov et al., Chem. Pharm. J. (1991) (Russian). 2:42-45
Links
| Product code | L6055 |
| Product name | AUSTRICINE |
| External Links |
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