BUNGAROTOXIN (beta-)
Product ID L8116-1MG 
Name BUNGAROTOXIN (beta-) 
Molecular formula β1 and β2 subunits
Description

It is a Phospholipase A2 composed of β1 subunit (120-amino acid) and β2 subunit (61-amino acid) linked by disulfide bridges


, from Bungarus multicinctus snake venom
Biological activity

As phospholipas A2, it is a selective inhibitor of the acetylcholine release at the neuromuscular junction.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 Unité(s) 152.00

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5 Unité(s) 608.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8116-1MG : unit price : free of charge
 Chemical and Physical Properties
Product code L8116-1MG  Molecular weight 20,500 Da (13,500 Da + 7,000 Da)
Product name BUNGAROTOXIN (beta-)  Physical form White solid
CAS No. 65862-89-7 & 82446-04-6 Melting point
RTECS EI6202000 & EI6202000 Solubility Well in water, saline and buffer (add saline or buffer after complete solubilization in water).
UNIPROT P00617;P00987 Optical Activity No optical Activity
PubChem SID    
PubChem CID    
Purity > 97% (PAGE analysis, FPLC)    
Toxicity(LD50) IVN-MUS LD50: 10 μg/kg
IPR-MUS LD50: 19 μg/kg
SCU-MUS LD50: 40 μg/kg
IMU-MUS LD50: 89 μg/kg
   
Chemical Name    
Storage & Reconstitution
Recommandations

Store at + 4°C
In solution, keep at - 20 °C


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8116-1MG 
Product name BUNGAROTOXIN (beta-) 

- Dreyer et al., "The actions of presynaptic snake toxins on membrane currents of mouse motor nerve terminals." J. Physiol. (1987). 386:445
- Chu Chen-Chung et al.,"The non-phospholipase A2 subunit of b-bungarotoxin plays an important role in the phospholipase A2-independent neurotoxic effect: characterization of three isotoxins with a common phospholipase A2 subunit." Biochem. J. 303(1):171(94
- Rowan et al., "Potassium channel blocking actions of b-bungarotoxin and related toxins on mouse and frog motor nerve terminals." Br. J. Pharmacol. (1988). 94:839
- Abe et al., "Isolation and characterization of presynaptically acting neurotoxins from the venom of Bungarus snakes." Eur. J. Biochem. (1977). 80:1
- Strong, "Potassium channel toxins." Pharmac. Ther. (1990). 46:137
 Links
Product code L8116-1MG 
Product name BUNGAROTOXIN (beta-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
UNIPROT
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