It is a semirigid molecular probe for different ion channels or receptors, specifically a Na⁺ channels blocker.
It represents a new class of anti-histaminic (nonH1 or H2) and anti 5-HT anti-allergic drugs: potential antagonist of H-3 histamine and serotonine (non 5-HT2) receptors.

It is also an anti-pruritic and a diamine oxidase activator.

Ion channels agent:
On Na⁺ channels (CA1-CA3 region of rat hippocampus neurons), 2.5x10^-4 M results in 100 % blocking effect, 2x10^-6 M in 50%.
On isolated throat ganglia neurons of the snail Limnea stagnalis (patch-clamp whole-cell recording):
* On K⁺ channels: meagre reversible blockade at 10^-5 M.
* No effect on Ca²⁺ or Cl^- channels.

Anti-allergic.
Non-sedative low anti-cholinergic anti-histaminic of prolonged action combined with anti-serotonine activity: aerosol histamine bronchoconstriction prevention in guinea-pig : 80-90 % at 2 mg/kg, the same for 5-HT : > 2 mg/kg. (Phencarol: 0.2 and 1 mg/kg respectively). Prolonged action (3-4 hours) and enhanced anti-5-HT activity compared to Phencarol (1.5 hours); efficient against itches. Non H-1, H-2 or 5-HT2 blocker: no binding to rat cortex H-1, H-2 receptors, 5-HT-2 receptors.

Low affinity to M-AChR.
pIC₅₀ [3H]-quinuclidinyl-3-benzylate, rat brain (M-1)/heart (M-2) 5.63/5.33; guinea pig ileum 4.9 (Methylfurmethide), 5.5 (ACh); Pridinol 7.3/6.8, Atropine 9.0/10.0.
Good penetration of biological membranes.
Diamine oxidase activator (75 mg/kg p.o., rat lung, 60 min +52%, 180 min +44%).
weak anti-AChE activity in vitro (human erythrocytes) Ki. 10⁴ = 2.60, type of inhibition: mixed competitive/non competitive.

Stable in dry state and solution (up to 150 °C).
Dissolves slowly, use heating or boiling. Solution for use: 10-3 M (2 mg in 5.01 ml).

Do not swallow, avoid extra-large quantity inhalation.
 For research use only — not intended for food, diagnostic or therapeutic use