Bj-xtrlT (recombinant)
Product ID L8223 
Name Bj-xtrlT (recombinant) 
Molecular formula
Description

It is an excitatory anti-insect selective scorpion beta-toxin.


Polypeptide of 76-amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in Eschirichia coli initialy from Buthotus judaicus scorpion venom.
Biological activity

It is toxic exclusively to insects with an effective dose 50% in blowfly larvae (ED50) of 14 ng/100 mg body weight. The equilibrium dissociation constant, Kd, has been determined in binding assays to cockroach neuronal membranes = 0.15 nM (ref. 3).

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 50ug 118.00

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1 Unité(s) 128.00

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5 x 50ug 472.00

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5 Unité(s) 512.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8223 : unit price : free of charge
 Chemical and Physical Properties
Product code L8223  Molecular weight 8,575 Da
Product name Bj-xtrlT (recombinant)  Physical form
CAS No. Melting point
RTECS Solubility In water and aqueous solutions
UNIPROT P56637 Optical Activity No optical Activity
PubChem SID    
PubChem CID    
Purity > 98 %    
Toxicity(LD50) No mammal toxicity    
Chemical Name    
Storage & Reconstitution
Recommandations

Store at 4°C


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8223 
Product name Bj-xtrlT (recombinant) 

- Froy, O., Zilberberg, N., Gordon, D., Turkov, M., Gilles, N., Stankiewicz, M., Pelhate, M., Loret, E., Oren, D., Shaanan, B. and Gurevitz, M. (1999) The putative bioactive surface of insect-selective scorpion excitatory neurotoxins. J.Biol.Chem. 274, 5769
- Oren, D. A., Froy, O., Amit, E., Kleinberger-Doron, N., Gurevitz, M. and Shaanan, B. (1998) An excitatory scorpion toxin with a distinctive feature: an additional a-helix at the C-terminus and its implications for interaction with insect sodium channels.
- Cohen, L., Karbat, I., Gilles, N., Froy, O., Angelovici, R., Gordon, D., Gurevitz, M.(2004) Dissect. of the functional surface of an anti-insect excit. toxin illuminates a putative 'hot spot' common to all scorpion beta-toxins affecting Na channels, J.Bi
 Links
Product code L8223 
Product name Bj-xtrlT (recombinant) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
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