Product ID L6031 
Name HYDRASTINE (D-beta-) 
Molecular formula C21H21NO6

It is a potent GABAA competitive antagonist, twice as potent as Bicuculline.

Phthalide isoquinoline alkaloid , from the plant Corydalis pseudoadunca, Fumariaceae.
Biological activity

D-beta Hydrastine acts as a competitive antagonist of GABA. GABA-activated currents, in rat isolated neurons, are strongly and reversibly blocked by an external application of D-beta Hydrastine and its effect is similar but twice as potent as that of D-Bicuculline.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
50 mg 75.00

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250 mg 375.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6031 : unit price : free of charge
 Chemical and Physical Properties
Product code L6031  Molecular weight 383.39 g/mol
Product name HYDRASTINE (D-beta-)  Physical form
CAS No. 118-08-1 Melting point 125-132 °C
RTECS MU6030000 Solubility In chloroform
Slightly in methanol and ethanol
Practically not in water
UNIPROT Optical Activity
PubChem SID    
PubChem CID 197835    
Purity 98 %    
Toxicity(LD50) IVN-MUS LD50: 0.102 mg/kg
SCU-MUS LD50: 0.96 mg/kg
Chemical Name (3S)-6,7-dimethoxy-3-[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one    
Storage & Reconstitution

Store at +4°C, in dark place.

Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 Bibliographic References
Product code L6031 
Product name HYDRASTINE (D-beta-) 

- Chernevskaja et al., "Inhibitions of the GABA-induced currents of rat neurons by the alkaloid isocoryne from the plant Corydalis pseudoadunca." Toxicon (1990). 28(6):727-730
Product code L6031 
Product name HYDRASTINE (D-beta-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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