Product ID L6088 
Molecular formula C11H14N2

It is an inhibitor of acetylcholinesterase and butyrilcholinesterase.

Indole alkaloid , from the plant Arundo donax, Gramineae.
Biological activity

1-10 mg/kg on narcotized cats lower for a short period the arterial pressure.
10-5 and 10-4 g/ml cause inhibition of the intestine tonus and of pendulum contractions of isolated part of the intestine.
It does not present any myotic activity, but it highly enhances the action of acetylcholine on the leech dorsal muscle and the frog ventral muscle.
In vitro, it inhibits acetylcholinesterase and butyrilcholinesterase. At 1/5,700 concentration, it lowers the brain and blood serum cholinesterase activity by 61 %.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
100 mg 32.00

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500 mg 128.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6088 : unit price : free of charge
 Chemical and Physical Properties
Product code L6088  Molecular weight 174.24 g/mol
Product name GRAMINE  Physical form Powder
CAS No. 87-52-5 Melting point 138-139 °C
RTECS NL7525000 Solubility In chloroform and ethanol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 6890    
Purity 97 % (TLC, mass spectrometry)    
Toxicity(LD50) IVN-MUS LD50: 73.5 mg/kg
SCU-MUS LD50: 215 mg/kg
IPR-RAT LD50: 155 mg/kg
Chemical Name 3-(Dimethylaminomethyl)indole    
Storage & Reconstitution

Store at +4°C, in dark place.

Savety Recommandations

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use

 Bibliographic References
Product code L6088 
Product name GRAMINE 

- Oreckov et al. Journal Organitcheskoy Khimii. (1937) (Russian). 7:63
- Oubaydoullayef et al. Chem. Nat. Comp. (1976). 553
- Sadritinov et al., "Pharmacology of vegetal alkaloids and their use in medecin." Meditsina (Tashkent), (1980) (Russian).
Product code L6088 
Product name GRAMINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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