Product ID L6029 
Molecular formula C17H13NO3

It is a CNS stimulant, convulsant and hypertensive.

Alkaloid , from plants of the Rutaceae family.
Biological activity

As CNS stimulant, it increases breath rhythm, reflex excitability and intensifies clinical cramps (tonic cramps).br>1 - 10 mg/kg increase arterial pressure by 5 - 20 mm Hg during 2 - 30 min.
1 - 3 - 5 mg/kg, on cats and dogs under anaesthesia, increase breath rhythm, which remains after decerebration, total excision of cerebellum and carotide ganglion block.
3 mg/kg and more, increase electric activity in the cortex and subcortex formations.
5 mg/kg remove completely the action of Thiopental sodium, Barbamil, Aminazine and Morphine on the bioelectrical activity of rabbit brain.
0.5 - 3mg/kg facilitate the conductivity of electric impulse in the downward activating system and stimulates the respiratory system of the reticulum formation of the caudal part of cat brain.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

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100 mg 520.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6029 : unit price : free of charge
 Chemical and Physical Properties
Product code L6029  Molecular weight 279.29 g/mol
Product name GRAVEOLINE  Physical form
CAS No. 485-61-0 Melting point 187-188 °C
RTECS Solubility In chloroform and hot alcohol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 353825    
Purity > 96%    
Toxicity(LD50) IPR-MUS LD50: 363.5 mg/kg    
Chemical Name 4(1H)-Quinolone,1-methyl-2-[3,4-(methylenedioxy)phenyl]- (6CI,7CI,8CI)    
Storage & Reconstitution

Store at +4°C, in dark place.

Savety Recommandations

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use

 Bibliographic References
Product code L6029 
Product name GRAVEOLINE 

- Ishmukamedov et al., "Foliosine influence on respiratory zones of reticular formation of caudal part of the brain." Pharmacology of alkaloids and glycosides. (1967) Tashkent p. 26-29 (Russian).
- Nasyrov et al., "EEG analysis of Foliosine alkaloid effect on the CNS." Rpts. Acad. Sci. UzSSR 2:51-53 (1968) (Russian).
Product code L6029 
Product name GRAVEOLINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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