HETERATISINE
Product ID L6061 
Name HETERATISINE 
Molecular formula C22H33NO5
Description

It is a potent antiarrhythmic and antifibrillatory. It is a Na+-channel blocker in cardiomyocytes.


C19-norditerpenoid alkaloid , from Aconitum heterophyllum of the Ranunculaceae family.
Biological activity

It has antiarrhythmic and antifibrillatory activity on experimental arrhythmias caused by Aconitine, calcium chloride, cardiac electric stimulation and artery occlusion. The active dosage ranges from 5 to 20 mg/kg in mammals.
Heteratisine is more active, more cardioselective and less toxic than Quinidine.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
10 mg 106.00

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50 mg 424.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6061 : unit price : free of charge
 Chemical and Physical Properties
Product code L6061  Molecular weight 391.5 g/mol
Product name HETERATISINE  Physical form Powder
CAS No. 3328-84-5 Melting point 259-260 °C
RTECS MK6800000 Solubility In chloroform and methanol
Not well in acetone and ethanol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 441735    
Purity 97 %    
Toxicity(LD50) IVN-MUS LD50: 180 mg/kg
IPR-MUS LD50: 430 mg/kg
   
Chemical Name 20-Ethyl-6beta,8-dihydroxy-1alpha-methoxy-4-methylheteratisan-14-one    
Storage & Reconstitution
Recommandations

Store at +4°C, in dark place.
20 mg of Heteratisine dissolve in 0.3 ml 3 % HCl.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6061 
Product name HETERATISINE 

- Pelletier et al., Phytochemistry (1968). 7:625
- Aneja et al., Tetrahedron (1973). 29:3297
 Links
Product code L6061 
Product name HETERATISINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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