Lqh II
Product ID L8217 
Name Lqh II 
Molecular formula
Description

It is a scorpion alpha-toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in mammals.


64-amino acid polypeptide with 4 disulfide bridges, , from Leiurus quinquestriatus hebraeus scorpion venom.
Biological activity

Lqh II is highly toxic and causes slowing and incomplete inactivation of the sodium currents. Except for the first and last amino acid residue, the sequence of Lqh II is identical to that of AaH II, a scorpion alpha-toxin from Androctonus australis Hector and has identical effects and binding properties on mammalian sodium channels.

 Packaging and Prices

Packaging Price (€) QuantitĂ© Buy Now
1 x 50ug 118.00

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5 x 50ug 472.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8217 : unit price : free of charge
 Chemical and Physical Properties
Product code L8217  Molecular weight 7235.4 Da
Product name Lqh II  Physical form
CAS No. Melting point
RTECS Solubility In water and saline
UNIPROT P59355 Optical Activity
PubChem SID    
PubChem CID    
Purity > 91%    
Toxicity(LD50)    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in freeze-dried state, store at +4°C


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8217 
Product name Lqh II 

- Sautière et al., (1998) Toxicon 36:1141-1154
- Gilles et al., (2000) Eur. J. Neurosci. 12:2823-2832
 Links
Product code L8217 
Product name Lqh II 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
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