L9066 - NMQ-OAc
NMQ-OAc | Product ID | L9066 |
| Name | NMQ-OAc |
| Molecular formula | C10H18INO2 |
| Description |
a weak muscarinic AChR agonist. Bicyclic analog of ACh. Poor penetration of biological membranes. Quaternary quinuclidine derivative, , synthetic. |
| Biological activity | 100-500 �g/kg i.v. in cats cause hypotension; in isolated rabbit intestine 6.4x10-4 M cause contractions; in frog isolated rectus abdominus ranges from 3.2x10-4 to 1.6x10-4 M cause slight contractions. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 690.00 | ||
| 100 mg | 2 760.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9066 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9066 | Molecular weight | 311.16 Da. |
| Product name | NMQ-OAc | Physical form | |
| CAS No. | 57345-44-5 | Melting point | 163-165 °C. |
| RTECS | Solubility | very soluble in water, ethanol. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 201718 | ||
| Purity | min. 98%. TLC ['Silufol UV-254', MeOH-NH3 (25%) 10:1 , Rf < 0.1; Rf of starting Q-Bn = 0.18. Visualization with Dragendorff's reagent]; NMR (in D2O). |
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| Toxicity(LD50) | mice (orally) 650mg/kg | ||
| Chemical Name | N-methyl- DL-3-acetoxyquinuclidinium iodide, 1-methyl- DL-3-acetoxyquinuclidinium iodide. | ||
| Storage & Reconstitution Recommandations |
store at room temperature in a dark place. Solution for use: dissolve in water: 10-3M (2 mg in 6.43 ml), stable for 1-2 days at 20°C. |
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| Savety Recommandations | Do not swallow or inhale; avoid eye and skin contact. |
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Bibliographic References
| Product code | L9066 |
| Product name | NMQ-OAc |
- Mashkovsky et al., Prog. Drug. Res. (1969). 13:294-339
- Wienstein et al., Molec. Pharmacol. (1975). 11(5):671-689
- Mashkovsky et al., Khim. Pharm. Zh. (1967) (Russian). (3):3
- Barlow et al., Molec. Pharmacol. (1975). 11(5):690-693
Links
| Product code | L9066 |
| Product name | NMQ-OAc |
| External Links |
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Toxicology Citations From PubMed
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