L8504-100UG - CONOTOXIN MVII C (Omega-)
(Syn. : SNX-230, omega-CgTx-MVIIC)
(Syn. : SNX-230, omega-CgTx-MVIIC)
CONOTOXIN MVII C (Omega-) | Product ID | L8504-100UG |
| Name | CONOTOXIN MVII C (Omega-) |
| Molecular formula | C106H178N40O32S7 |
| Description |
It is a blocker of omega-conotoxin GVIA-insensitive Ca2+ channels, including P-type Ca2+-channels in cerebellar Purkinge cells. A 26-amino acid peptide with 3 disulfide bridges , synthetic, originally from Conus magus molluscan venom |
| Biological activity | ω-CgTx-MVIIC inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of Omega-CgTx-GVIA-resistant currents in hippocampal CA1 neurons. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 110.00 | ||
| 5 Unité(s) | 440.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8504-100UG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8504-100UG | Molecular weight | 2749.25 Da |
| Product name | CONOTOXIN MVII C (Omega-) | Physical form | white powder |
| CAS No. | 147794-23-8 | Melting point | |
| RTECS | Solubility | In water, saline. | |
| UNIPROT | P37300 | Optical Activity | |
| PubChem SID | |||
| PubChem CID | 56841670 | ||
| Purity | > 99%. Reverse phase HPLC, capillary electrophoresis | ||
| Toxicity(LD50) | |||
| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable in freeze-dried state. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L8504-100UG |
| Product name | CONOTOXIN MVII C (Omega-) |
- Hillyard et al., "A new Conus peptide ligand for mammalian presynaptic Ca2+ channels." Neuron (1992). 9:69-77
Links
| Product code | L8504-100UG |
| Product name | CONOTOXIN MVII C (Omega-) |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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PubChem CID
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 UNIPROT |
