PLA2 Apis mellifera
Product ID L8408 
Name PLA2 Apis mellifera 
Molecular formula C664H1012N186O202S13
Description

It is the main antigen of bee venom, causing hydrolysis of erythrocytes and mast cells membrane phospholipids, and acting in synergy with Melittin.


134-amino acid protein with 5 disulfite bonds , from Apis mellifera bee venom.
Biological activity

It has an effect at more than 850 units/mg protein at pH 8.9 at 25 °C., using egg yolk phosphatidylcholine.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 1mg 51.00

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5 x 1mg 204.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8408 : unit price : free of charge
 Chemical and Physical Properties
Product code L8408  Molecular weight ~ 18,500 Da
Product name PLA2 Apis mellifera  Physical form
CAS No. Melting point
RTECS SZ6114950 Solubility In water
UNIPROT P00630 Optical Activity
PubChem SID    
PubChem CID    
Purity > 96 % (HPLC)    
Toxicity(LD50) IPR-MUS LD50: 5 mg/kg
SCU-MUS LD50: 1200 µg/kg
IVN-MUS LD50: 7500 µg/kg
   
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in dried state;

Store at 4 °C.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8408 
Product name PLA2 Apis mellifera 

- Hollander et al., "Characterization of the oligosaccharide structures on bee venom phospholipase A2." Carbohydrate Research (1993). 247:291-297
- Kubelka et al., "Primary structures of the N-linked carbohydrate chains from honeybee venom phospolipase A2." European Journal of Biochemistry (1993). 213(3):1193-1204
- Prenner et al., "The antigenicity of the carbohydrate moiety of an insect glycoprotein, honey-bee (Apis mellifera) venom phospholipase A2: the role of alpha 1,3-fucosylation of the asparagine-bound N-acetylglucosamine." Biochemical Jl (London 1984) (1992)
- Slotta et al., "Enzymatic and toxic activity of phospholipase A." in A. De Vries and E. Kochva, Eds., Toxins of Animal and Plant Origin, Vol. I, Gordon and Breach, New-York (1971), 401-418.
 Links
Product code L8408 
Product name PLA2 Apis mellifera 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
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