L9035-2MG - Q° Me
Q° Me | Product ID | L9035 |
| Name | Q Me |
| Molecular formula | C8H16IN |
| Description |
a rigid bicyclic analog of TMA and TEA. Molecular probe for calibration of the size of ion channels or receptors sites. Nicotinic AChR blocker. Acetylcholinesterase inhibitor. Lipid layers modifier. Quaternary quinuclidine derivative, , synthetic. |
| Biological activity | Nicotinic AChR: less active than Tetraethylammonium (TEA) and Tetramethylammonium (TMA). Acetylcholinesterase: Ki TMA=1.87 mM, Ki TEA=1.04 mM, Ki QMe=0.12 mM [2]. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 690.00 | ||
| 100 mg | 2 760.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9035-2MG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9035 | Molecular weight | 253.13 Da. |
| Product name | Q Me | Physical form | yellowish crystal powder. |
| CAS No. | 45651-41-0 | Melting point | > 269-273 °C. |
| RTECS | Solubility | very soluble in water, ethanol. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
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| Purity | min. 98%. (NMR (D2O)) | ||
| Toxicity(LD50) | mice (orally): 200 mg/kg | ||
| Chemical Name | 1-methyl quinicludinium iodide, N-methyl quinuclidinium iodide. | ||
| Storage & Reconstitution Recommandations |
store at room temperature in a dark place, in a dessicator (extremely hygroscopic). Solution for use: dissolve in water: 10-3M (2 mg in 7.91 ml), stable for 1-2 days at 20°C. |
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| Savety Recommandations | Do not swallow or inhale; avoid eye and skin contact. | ||
Bibliographic References
| Product code | L9035 |
| Product name | Q Me |
- Lukec R. et al., Chem. Listy (1955). 49: 510-508
- Kellet Jr., J. Pharm. Sci. (1965). 54 (3): 883-887
- Kellet Jr., J. Pharm. Sci. (1966). 55 (3): 414-417
Links
| Product code | L9035 |
| Product name | Q Me |
| External Links |
PubMed
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Toxicology Citations From PubMed
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