QUIRESTON
Product ID L9039 
Name QUIRESTON 
Molecular formula C8H14INO
Description

a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes; acetylcholine synthesis inhibitor; weak penetration of biological membranes.


Quinicludine derivative, , synthetic.
Biological activity

cell impermeable inhibitor of high-affinity choline uptake (HAChU). For comparative information see the attached table.
poor penetration of biological membranes.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 530.00

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100 mg 2 120.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L9039 : unit price : free of charge
 Chemical and Physical Properties
Product code L9039  Molecular weight 267.11 Da.
Product name QUIRESTON  Physical form slightly yellowish crystal powder.
CAS No. 6659-51-4 Melting point 275-277 °C.
RTECS Solubility water, ethanol and DMSO.
UNIPROT Optical Activity
PubChem SID    
PubChem CID 201716    
Purity min. 99.5%. (NMR (D2O)).    
Toxicity(LD50) mice (orally) >500 mg/kg    
Chemical Name 3-quinuclidon methoiodide; 1-methyl-3-oxoquinuclidium iodide.    
Storage & Reconstitution
Recommandations

store in a dark place in a dessicator; solutions are stable for 1-2 days at room temperature. Solution for use: 10-3M (2 mg in 7.49 ml).


 
Savety Recommandations  
 Bibliographic References
Product code L9039 
Product name QUIRESTON 

- Dahlbom R. et al., "Cell Mol. Basis Cholinergic Funct.", Dowdall M. J. and Hawthorne J. N. Eds., Horwood, Chichester U.K., (1987) 347-354
- Sterling et al., "Inhibition of high-affinity choline uptake and acetylcholine synthesis by quinuclidinyl and hemicholinium derivatives", J. Neurochem.(1986). 46(14):1170-1175
- Doukas P.H. et al., ibid, 355-1175
- Baltzod F. et al., Biochem. Pharm. (1980). 29(18):2413-2416
- Tamaru M. et al., Brain Res (1988). 473(2):205-226
- Dowdall M.J. et al., in Cholinergic mechanisms and Psycopharmacology, Ed. D.J.Jenden, Plenum Press, N-Y, (1978). 359
 Links
Product code L9039 
Product name QUIRESTON 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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