TADJAKONINE
Product ID L6098 
Name TADJAKONINE 
Molecular formula C31H35NO7
Description

It is a stong antiarrhythmic and a local anesthetic as potent as Cocaine.


C20-diterpenoid alkaloid , from plants of the Ranunculaceae family
Biological activity

ED50s/sub> for arrhythmias caused by Aconitine: 0.3 mg/kg. 10-5 M block TTX-sensitive Na+ channels on rat isolated sensorial ganglion neurons (F. N. Djakhangirov and E. A. Valeev, unpublished).

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

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100 mg 416.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6098 : unit price : free of charge
 Chemical and Physical Properties
Product code L6098  Molecular weight 533.61 g/mol
Product name TADJAKONINE  Physical form
CAS No. 11087-94-8 Melting point 248-249 °C (decomp. acetone)
RTECS Solubility In chloroform,
Moderately in ethanol
Not well in acetone
UNIPROT Optical Activity
PubChem SID    
PubChem CID 6713971    
Purity > 97%    
Toxicity(LD50) IVN-RAT LD50: 12.8 mg/kg    
Chemical Name    
Storage & Reconstitution
Recommandations

- for experiments on Tadjakonine local anesthetic activity: 0.25-0.5 % aqueous solution;

- for in vitro experiments: 10-9-10-8 M;

- to prepare a 1 % aqueous solution of Tadjakonine: dissolve 20 mg of Tadjakonine in 0.3 ml 3 % HCl. Then, dilute this solution in water up to obtaining 2 ml of total solution.

Store at +4°C, in dark place.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6098 
Product name TADJAKONINE 

- Yussupova et al., Chem. Nat. Comp. (1992).p. 382
 Links
Product code L6098 
Product name TADJAKONINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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