TEMPIDOL
Product ID L9058 
Name TEMPIDOL 
Molecular formula C9H19NO.HCl
Description

a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Secondary analog of Pempidol. Antioxidant, radical scavenger.


Piperidine derivative, , synthetic.
Biological activity

For comparative information see the attached 2 tables.

Cell permeant central nicotinic cholinoreceptor blocker without action on skeleton muscle innervation.

Antioxidant (precursor of stable TEMPO nitroxyl radical): together with PEMPIDOL can be used for testing the possibility of antioxydant contribution into any observed biological activity of TEMPIDOL.

Potential antimitotic (ask for the TEMPIDONE data).

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 2mg 34.00

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5 x 2mg 136.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L9058 : unit price : free of charge
 Chemical and Physical Properties
Product code L9058  Molecular weight 193.71 Da.
Product name TEMPIDOL  Physical form colorless crystal powder.
CAS No. 24303-88-5 (base), 79316-86-2 (HCl). Melting point decomp. >315 °C.
RTECS Solubility water, ethanol.
UNIPROT Optical Activity
PubChem SID    
PubChem CID 18985122    
Purity min. 98%.
TLC (Silufol UV-254, MeOH:NH3(25%) Rf 0.53, development with Dragendorff� reagent); NMR (D2O).
   
Toxicity(LD50)    
Chemical Name 2,2,6,6-tetramethylpiperidinol-4 hydrochloride.    
Storage & Reconstitution
Recommandations

store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 10.31 ml), stable for 1-2 days at 20°C.


 
Savety Recommandations

do not swallow or inhale; avoid eye and skin contact.

 
 Bibliographic References
Product code L9058 
Product name TEMPIDOL 

- Brehteric et al., Nature (1959). 184:1707-1709
 Links
Product code L9058 
Product name TEMPIDOL 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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