VERATROYLZYGADENINE
Product ID L6077 
Name VERATROYLZYGADENINE 
Molecular formula C36H51NO10
Description

As an analog of Veratridine, it is a Na+ channel activator and a potent neurotoxic. Indeed, it is a depolarizing agent on membranes of nerve terminal, muscle and gland cells.


Steroid alkaloid , from plants of the Veratrum genus, Liliaceae
Biological activity

It has an effect on cardiac vessel system at the dosage of 1-50 μg/kg (i.v.)

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 80.00

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100 mg 320.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6077 : unit price : free of charge
 Chemical and Physical Properties
Product code L6077  Molecular weight 657.79 g/mol
Product name VERATROYLZYGADENINE  Physical form
CAS No. 31329-58-5 Melting point 259-261 °C
RTECS FL5660000 Solubility In chloroform and methanol pyridine
Not well in ethanol, chloroform, water, acetone
UNIPROT Optical Activity
PubChem SID    
PubChem CID 35772    
Purity ≥ 96 % (TLC, mass spectrometry)    
Toxicity(LD50) mice (i.v.): 0.77 (0.66-0.89) mg/kg, (s.c): 9.2 (8.1-10.5) mg/kg    
Chemical Name 4,9-Epoxycevane-3-beta,4-beta,14,15-alpha,16-beta,20-hexol 3-veratrate    
Storage & Reconstitution
Recommandations

Store at +4°C, in dark place.
Stable in freeze-dried state. Stable several months in solution.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6077 
Product name VERATROYLZYGADENINE 

- Kupchan. "Veratrum alkaloids. XXX. The structure and configuration of zygadenine." J. Amer. Chem. Soc. (1959). 81:1925
- Fink et al., "Veratridine and other depolarizing agents counteract the inhibitory effect of Mg++ ion..."Nannyn-Schmiedeberg’s Arch. Pharmacol. (1990). 342N(1):53-60
- Tarvin et al., "Glucose induced electrical activity in the pancreatic beta-cells: effect of veratridine." Amer. J. Physiol. (1981). 240:127-134
- Honerjager, "A neutrally mediated inotropic effect of veratridine and sevadine on isolated guinea pig papillary muscle." Nannyn Schmiederberg's Arch. Pharmacol. (1980). 314:157-160
 Links
Product code L6077 
Product name VERATROYLZYGADENINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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