DENDROTOXIN (Alpha-)
Product ID L8106 
Name DENDROTOXIN (Alpha-) 
Molecular formula
Description
59-amino acid peptide with 3 disulfide bridges , from Dendroaspis angusticeps snake venom.
Biological activity

A toxin which facilitates synaptic transmission at the neuromuscular junction and has been shown to block a 4-AP-sensitive, inactivating, voltage-gated K+ current.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 x 100ug 137.00

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5 x 100ug 548.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8106 : unit price : free of charge
 Chemical and Physical Properties
Product code L8106  Molecular weight 7,071 Da
Product name DENDROTOXIN (Alpha-)  Physical form
CAS No. 74504-53-3 Melting point
RTECS Solubility In water and saline
UNIPROT P00980 Optical Activity
PubChem SID    
PubChem CID    
Purity > 98% (HPLC)    
Toxicity(LD50)    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in freeze-dried state.

In solution, keep at -20°C.


 
Savety Recommandations  
 Bibliographic References
Product code L8106 
Product name DENDROTOXIN (Alpha-) 

- Harvey et al., "Protease inhibitor homologues from mamba venoms: facilitation of acetylcholine release and interactions with prejunctionnal blocking toxins." Br. J. Pharmacol. 1982 77:153-161
- Halliwell et al., "Central action of Dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors." Proc. Natl. Acad. Sci. USA (1986). 83:493-497
- Stansfeld et al., "4-Aminopyridine and Dendrotoxin induce repetitive firing in rat visceral sensory neurons by blocking slowly inactivating outward current." Neurosci. Lett.(1986). 64:299-304
- Harvey et al., "Dendrotoxin from the venom of the green mamba, Dendroaspis angusticeps: a neurotoxin that enhances acetylcholine release at neuromuscular junctions." Naunyn-Schmiedeberg's Arch. Pharmacol. (1980). 312:1-6
- Benishin et al., Molecular Pharmacology(1988). 34:152-159
 Links
Product code L8106 
Product name DENDROTOXIN (Alpha-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
UNIPROT
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